Hereditary Angioedema

The following information will help answer some of your questions about hereditary angioedema. It'll also provide information about the different ways to treat hereditary angioedema.

What is hereditary angioedema?

Hereditary angioedema, or HAE, is a rare and serious problem with the immune system that's usually passed down from parents to children. It causes severe swelling, most commonly in the arms and legs, face, stomach and airways. About one in three people with HAE may develop a non-itchy rash during an attack. Symptoms usually start when you're a child, get worse around puberty, and continue throughout life.

What causes HAE?

HAE is caused when a person has low levels of a protein called C1 inhibitor or has C1 inhibitor that doesn't work. The lack of this protein affects the blood vessels, allowing fluids to leak out into body tissues, causing swelling. Minor trauma (like dental procedures or surgery), illness or stress may trigger an attack, but swelling often occurs without a known trigger.

How is HAE treated?

There is no cure for HAE, and symptoms aren't the same for every person. Work with your doctor to create a personalized treatment plan that best helps you lead a healthy life.

Medications are available that can help prevent and/or treat HAE attacks. Your doctor may prescribe either intravenous (infused into the vein) medications, or subcutaneous (injected under the skin) medications to help treat this condition.

For more information about HAE, call your BriovaRx pharmacist or one of the resources listed below: